Syphilis is a systemic infectious disease caused by Treponema pallidum. Early Syphilis is not life threatening, but late manifestations affect the life span and patient’s productivity. Untreated primary infections in the mother affect the fetus.\nState of disease % Positivity\nPrimary Syphilis 80-90\nSecondary Syphilis 99-100\nTertiary Syphilis 98\nThis test is used for confirmation of syphilis due to its high sensitivity and specificity.\n